The powerful combination of genetic, developmental and molecular approaches possible with the fruit fly, Drosophila melanogaster, has led to a profound understanding of the genetic control of early developmental events. However, Drosophila is a highly specialized long germ insect, and the mechanisms controlling its early development may not be typical of insects or Arthropods in general. The beetle, Tribolium castaneum, offers a similar opportunity to integrate high resolution genetic analysis with the developmental/molecular approaches currently used in other organisms. Early results (...) document significant differences between insect orders in the functions of genes responsible for establishing developmental commitments. (shrink)

Red List details the ‘Other History’ of MI5’s activities between WWI and the end of the Cold War. Not that of counter-Soviet and counter-Irish Republican espionage, but the pursuit of British intel...

Recently a growing number of biologists have begun to consider the causal role that processes of embryonic development may play in evolution. This constitutes a reunion of these phenomena which had been linked in the nineteenth century through Haeckel's biogenetic law. This reunion may result in a new subdiscipline of biology, if there is a set of unique concepts and methods which tie the various research approaches together. Such concepts as bauplan, canalization, and developmental constraint, may serve in such a (...) capacity. The methods employed must combine comparative and experimental analyses, with special attention paid to the range of variation in developmental events within each taxon. These concepts and methods are also applicable to the problem of how development evolved, thus the evolution of development may also be considered part of the reunion. The reunion is discussed in terms of the potential participation of various schools of thought found in the current literature. (shrink)

Studies on the Archaeology of Ebla, 1980-2010. By Paolo Matthiae, edited by Frances Pinnock. Wiesbaden: Harrassowitz Verlag, 2013. Pp. xi + 664, 226 plts. €98.

A major concern of public health authorities is to also encourage adults to be exposed to enriched environments during the pandemic lockdown, as was recently the case worldwide during the COVID-19 outbreak. Games for adults that require physical activity, known as exergames, offer opportunities here. In particular, the output of the gaming industry nowadays offers computer games with extended reality which combines real and virtual environments and refers to human-machine interactions generated by computers and wearable technologies. For example, playing the (...) game in front of a computer screen while standing or walking on a force plate or treadmill allows the user to react to certain infrastructural changes and obstacles within the virtual environment. Recent developments, optimization, and minimizations in wearable technology have produced wireless headsets and sensors that allow for unrestricted whole-body movement. This makes the virtual experience more immersive and provides the opportunity for greater engagement than traditional exercise. Currently, XR serves as an umbrella term for current immersive technologies as well as future realities that enhance the experience with features that produce new controllable environments. Overall, these technology-enhanced exergames challenge the adult user and modify the experience by increasing sensory stimulation and creating an environment where virtual and real elements interact. As a therapy, exergames can potentially create new environments and visualizations that may be more ecologically valid and thus simulate real activities of daily living that can be trained. Furthermore, by adding telemedicine features to the exergame, progress over time can be closely monitored and feedback provided, offering future opportunities for cognitive-motor assessment. To more optimally serve and challenge adults both physically and cognitively over time in future lockdowns, there is a need to provide long-term remote training and feedback. Particularly related to activities of daily living that create opportunities for effective and lasting rehabilitation for elderly and sufferers from chronic non-communicable diseases. The aim of the current review is to envision the remote training and monitoring of physical and cognitive aspects for adults with limited mobility, through the implementation of concurrent telehealth and exergame features using XR and wireless sensor technologies. (shrink)

Definitions are traditionally seen as abbreviations, as tools for notational convenience that do not increase inferential power. From a Philosophy of Mathematical Practice point of view, however, there is much more to definitions. For example, definitions can play a role in problem solving, definitions can contribute to understanding, sometimes equivalent definitions are appreciated differently, and so on. This chapter reviews the literature on definitions and (to a certain extent) concepts in mathematical practice. It is structured according to four themes through (...) which definitions (and concepts) in mathematical practice have been studied. These themes concern (1) the nature of definitions, (2) whether and how concepts evolve, (3) definitions and concepts from a communal perspective, and (4) different values relating to definitions and concepts. (shrink)

The Many-Interacting-Worlds (MIW) approach to a quantum theory without wave functions proposed in [8] leads naturally to numerical integrators of the Schrödinger equation on comoving grids. As yet, little is known about concrete MIW models for more than one spatial dimension and/or more than one particle. In honour of Detlef Dürr, we report on a further development of the MIW approach to treat arbitrary degrees of freedom and provide a numerical proof of concept for ground states in 2d. The latter (...) is part of a systematic numerical study [22] that includes also 1d ground and excited states. With this step towards the treatment of higher degrees of freedom we hope to stimulate their further study. (shrink)

James Burnett, Lord Monboddo’s (1714–1799) contribution to Scottish Enlightenment thinking on race is regularly held to be twofold. As a Lord of Session, he supposedly defended slavery on Aristotelian grounds, infamously voting against Joseph Knight’s freedom in Knight v. Wedderburn (1778). In his philosophical writings, Monboddo is known for his arguments in favour of the humanity of orangutangs, which scholars have claimed informed both his own views on slavery and also wider apologetics for the trade. At the same time, Monboddo (...) is frequently cited as providing a fulsome defence of the achievements of black Africans against Hume’s footnote in ‘Of Natural Characters’ (added in 1753). The full significance of Monboddo’s counterexample to Hume’s claims, the civilization of black ancient Egypt, has not been adequately understood. In this article I undertake a deep dive into Monboddo’s views on race, slavery, and the black origins of civilization present in his largely ignored six-volume Antient Metaphysics (1779–1799). The arguments that emerge show that Monboddo was not quite the apologist for enslaving black Africans as he is sometimes presented as being, but also that his thought was far from the enlightened Scottish mainstream. (shrink)

In France, as in other European countries, especially Britain and Germany, the nineteenth century was a period of great progress and achievement in science. This would still have been true if Claude Bernard and Louis Pasteur had been the only outstanding French scientists of the nineteenth century, whereas there were, of course, many others apart from an impressive number of brilliant French mathematicians. Nevertheless, although it was a great century for French science there was perhaps something rather disappointing about it, (...) and something rather ingrowing about the attitude of French scientists towards scientific developments in other countries. For example, the French took it hard that the creator of the theory of evolution should have been an Englishman, remembering too late Darwin's predecessor Lamarck, and they certainly were very slow in accepting Darwin's theory of evolution.1 Again, the French may have felt that after the important contributions of French scientists such as Coulomb, Poisson, Biot and, above all, Ampère, the theory of electricity and magnetism which is today principally associated with the names of Faraday and Maxwell should have been created by a Frenchman. Once again this new theory was only accepted very slowly and hesitantly, and even unwillingly, in France—one thinks, for example, of the criticisms levelled at the theory by Pierre Duhem in his “The Aim and Structure of Physical Theory”.2 Of course it might be that if one knew how to weigh properly the various achievements of French scientists in different branches of science one would find that, allowing for her rather static population during the nineteenth century, thetotalcontribution of France compared well with those of Britain and Germany. Nevertheless, in one case at least, that of theoretical physics, there seems to have been an unmistakable failure to live up to the promise of the beginning of the century. The purpose of this paper is to advance possible reasons to explain this failure. (shrink)

The tradition that Socrates had two wives at once, Xanthippe and Myrto, though an established one among ancient scholars, has met with blank incredulity in modern times. It impugns the character of Socrates, who has been established by Plato's martyrology as the unimpeachable patron saint of Western philosophy. And it appears to cast a slur on Greek marriage—not that the guiding lines of this somewhat ramshackle institution are perfectly known.

We are living through a cultural moment in which strident criticisms are being made of the ethical validity and utility of the discipline of the history of political thought (H.P.T.). While not alo...